Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes

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Image Analysis, Machine Vision, Data Science +8

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.2K citations

Inflammation, Signal Transduction, Signaling Pathway +12

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Nobuhiko Kayagaki, Irma B. Stowe, Bettina L. Lee et al. · Nature · 2015 · 3.5K citations

Inflammation, Anti-inflammatory, Signal Transduction +8

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Xing Liu, Zhibin Zhang, Jianbin Ruan et al. · Nature · 2016 · 3.1K citations · Full text

Inflammation, Apoptosis, Cell Death +7

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

Yupeng Wang, Wenqing Gao, Xuyan Shi et al. · Nature · 2017 · 3K citations

Medicine, Apoptosis, Pyroptosis +9