Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner

Stephanie A. Conos, Kaiwen Chen, Dominic De Nardo, +10

Proceedings of the National Academy of Sciences

ApoptosisImmunologyImmune RegulationCell DeathInnate Immunity +24

Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity

Hideki Hara, K. Tsuchiya, Ikuo Kawamura, +7

Nature Immunology

Adaptor AscSignal TransductionSignaling PathwayMedicineMolecular Biology +7

The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection

Hideki Hara, Sergey S. Seregin, Dahai Yang, +6

Cell

InflammationPathogenesisImmunologyInnate Immune SystemInflammasome +4

Cutting Edge: Nitric Oxide Inhibits the NLRP3 Inflammasome

Eduardo Hernández-Cuellar, K. Tsuchiya, Hideki Hara, +5

The Journal of Immunology

Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to <i>Streptococcus pneumoniae</i> Infection

Rendong Fang, K. Tsuchiya, Ikuo Kawamura, +12

The Journal of Immunology

Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes

K. Tsuchiya, Shoko Hosojima, Hideki Hara, +4

Cell Reports

Serial computed tomographic evaluation in desquamative interstitial pneumonia

Masanori Akira, Satoshi Yamamoto, Hideki Hara, +2

Thorax

IL-22 controls iron-dependent nutritional immunity against systemic bacterial infections

Kei Sakamoto, Yun‐Gi Kim, Hideki Hara, +7

Science Immunology

Mechanisms of age-related decline in antigen-specific T cell proliferative response: IL-2 receptor expression and recombinant IL-2 induced proliferative response of purified tac-positive T cells

Shigeru Negoro, Hideki Hara, Susumu Miyata, +5

Mechanisms of Ageing and Development

InflammationAge-related DeclineAutoimmune DiseaseRecombinant Il-2T-regulatory Cell +11

Thin-Section CT Findings in Rheumatoid Arthritis-Associated Lung Disease: CT Patterns and Their Courses

Masanori Akira, Mitsunori Sakatani, Hideki Hara

Journal of Computer Assisted Tomography