Alzheimer’s disease brain contains tau fractions with differential prion-like activities

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

Inge Grundke‐Iqbal, Khurshid Iqbal, Y C Tung et al. · Proceedings of the National Academy of Sciences · 1986 · 3.6K citations · Full text

Molecular Biology, Cytoskeleton, Microtubule-associated Protein Tau +19

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

Bradley T. Hyman, Creighton H. Phelps, Thomas G. Beach et al. · Alzheimer s & Dementia · 2012 · 3.1K citations · Full text

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

Paulina V. Arriagada, John H. Growdon, E. Tessa Hedley‐Whyte et al. · Neurology · 1992 · 2.7K citations

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

Heiko Braak, Dietmar Rudolf Thal, Estifanos Ghebremedhin et al. · Journal of Neuropathology & Experimental Neurology · 2011 · 2.2K citations · Full text

Sporadic Alzheimer Disease, Aging, Brain Development +25

Transmission and spreading of tauopathy in transgenic mouse brain

Florence Clavaguera, Tristan Bolmont, R. Anthony Crowther et al. · Nature Cell Biology · 2009 · 1.8K citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Xenotransplantation +7