Concepedia

Tau Oligomerization

Tau Oligomerization is a pathological biochemical process in which hyperphosphorylated tau proteins associate into small, soluble multimeric aggregates, distinguishing it from other tau aggregation states by its intermediate oligomeric structure and high neurotoxic potential in neurodegenerative tauopathies.

1.1K

Publications

114.6K

Citations

5.9K

Authors

1.3K

Institutions

Publications per year

2017–2026

422

Parents

Publications

1.1K

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

Maj-Linda B. Selenica, Milene L. Brownlow, Jeffy P. Jimenez et al. · Neurodegenerative Diseases · 2012 · 10.4K citations · Full text

, , +17

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

Michel Goedert, Maria Grazia Spillantini, Ross Jakes et al. · Neuron · 1989 · 2.5K citations

, , +16

Cryo-EM structures of tau filaments from Alzheimer’s disease

Anthony W. P. Fitzpatrick, Benjamin Falcon, Shaoda He et al. · Nature · 2017 · 2.1K citations

, , +16

Primary age-related tauopathy (PART): a common pathology associated with human aging

John F. Crary, John Q. Trojanowski, Julie A. Schneider et al. · Acta Neuropathologica · 2014 · 1.5K citations · Full text

, , +14

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

Jada Lewis, Eileen McGowan, Julia M. Rockwood et al. · Nature Genetics · 2000 · 1.4K citations

, , +16

1–5 of 1.1K

Authors

5.9K

  1. RK
    Rakez Kayed

    The University of Texas Medical Branch at Galveston, United States

    37 publications · 5.2K citations

    32

    h-index

  2. JÁ
    Jesús Ávila

    Centro de Biología Molecular Severo Ochoa, Spain

    27 publications · 1.8K citations

    24

    h-index

  3. US
    Urmi Sengupta

    The University of Texas Medical Branch at Galveston, United States

    21 publications · 3.1K citations

    21

    h-index

  4. JQ
    John Q. Trojanowski

    University of Pennsylvania, United States

    20 publications · 3.8K citations

    20

    h-index

  5. EM
    Eckhard Mandelkow�

    Max Planck Unit for Structural Molecular Biology, Germany

    21 publications · 4.1K citations

    20

    h-index

1–5 of 5.9K

Institutions

1.3K

  1. The University of Texas Medical Branch at Galveston

    Galveston, United States

    31 h-index

    185 publications

    24.7K citations

  2. Harvard University

    Cambridge, United States

    31 h-index

    193 publications

    36.6K citations

  3. Mayo Clinic in Florida

    Jacksonville, United States

    31 h-index

    118 publications

    48.4K citations

  4. Inserm

    Paris, France

    28 h-index

    167 publications

    18.9K citations

  5. University of Pennsylvania

    Philadelphia, United States

    27 h-index

    150 publications

    20.5K citations

  6. Northwestern University

    Evanston, United States

    26 h-index

    91 publications

    14.5K citations

  7. Michigan State University

    East Lansing, United States

    25 h-index

    78 publications

    6.3K citations

  8. German Center for Neurodegenerative Diseases

    Bonn, Germany

    25 h-index

    117 publications

    15.4K citations

1–8 of 1.3K

Venues

  1. Neurobiology of Aging

    60 publications · 5.7K citations

    42

    h-index

  2. Journal of Biological Chemistry

    JBC · 46 publications · 6.5K citations

    37

    h-index

  3. Acta Neuropathologica

    46 publications · 5.6K citations

    36

    h-index

  4. Journal of Alzheimer s Disease

    JAD · 43 publications · 2.6K citations

    30

    h-index

  5. Neurobiology of Disease

    38 publications · 2.7K citations

    30

    h-index

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