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UBXN7 cofactor of CRL3KEAP1 and CRL2VHL ubiquitin ligase complexes mediates reciprocal regulation of NRF2 and HIF-1α proteins

Jacopo Di Gregorio, Lucia Cilenti, Camilla T. Ambivero, Thomas Andl, Ronglih Liao, Antonis S. Zervos

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2021 · 35 citations · 44 references

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44

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang et al. · Nature · 1999 · 5.2K citations

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The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Masaaki Komatsu, Satoshi Waguri, Keiko Taguchi et al. · Nature Cell Biology · 2010 · 2.4K citations

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Mitochondrial electron transport chain, ROS generation and uncoupling (Review)

Ruzhou Zhao, Shuai Jiang, Lin Zhang et al. · International Journal of Molecular Medicine · 2019 · 1.4K citations · Full text

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Genome-Wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle's Dynamics and Signaling

Wei Li, Mário Henrique Bengtson, Axel Ulbrich et al. · PLoS ONE · 2008 · 840 citations · Full text

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