Meloxicam methyl group determines enzyme specificity for thiazole bioactivation compared to sudoxicam

Effect of common organic solvents on in vitro cytochrome P450-mediated metabolic activities in human liver microsomes.

Nathalie Chauret, Annick Gauthier, Deborah A. Nicoll‐Griffith · PubMed · 1998 · 310 citations

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Indirect and nonmedical costs among people with rheumatoid arthritis and osteoarthritis compared with nonarthritic controls.

S. E. Gabriel, C. S. Crowson, Mary E. Campion et al. · PubMed · 1997 · 192 citations

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Effects of organic solvents on the activities of cytochrome P450 isoforms, UDP-dependent glucuronyl transferase, and phenol sulfotransferase in human hepatocytes.

Judy D. Easterbrook, C. Lu, Y Sakai et al. · PubMed · 2001 · 192 citations

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Simultaneous Absolute Quantification of 11 Cytochrome P450 Isoforms in Human Liver Microsomes by Liquid Chromatography Tandem Mass Spectrometry with In Silico Target Peptide Selection

Hirotaka Kawakami, Sumio Ohtsuki, Junichi Kamiie et al. · Journal of Pharmaceutical Sciences · 2010 · 165 citations

Pharmacy, Biochemistry, Pharmacology +15

Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?

Ai‐Ming Yu, Robert L. Haining · PubMed · 2001 · 136 citations

Medicine, Pharmacokinetics, Pharmacology +16