Concepedia

Methyl Group Replacement

Methyl Group Replacement is a chemical modification strategy in which a methyl group is systematically substituted with a structurally or functionally distinct moiety to modulate the physicochemical or biological properties of a molecule within the context of atom replacement and functional group substitution.

639

Publications

25.7K

Citations

3.1K

Authors

778

Institutions

Publications per year

2017–2026

64

Parents

Publications

639

Site-Specific Modification of Pre-mRNA: the 2′-Hydroxyl Groups at the Splice Sites

Melissa J. Moore, Phillip A. Sharp · Science · 1992 · 469 citations

, , +17

Methyl Effects on Protein–Ligand Binding

Cheryl S. Leung, Siegfried S. F. Leung, Julian Tirado‐Rives et al. · Journal of Medicinal Chemistry · 2012 · 399 citations

, , +17

Novel properties of ionic liquids in selective sulfur removal from fuels at room temperature

Shuguang Zhang, Z. Conrad Zhang · Green Chemistry · 2002 · 271 citations

, , +13

THE METHYL FOLATE TRAP A physiological response in man to prevent methyl group deficiency in kwashiorkor (methionine deficiency) and an explanation for folic-acid-induced exacerbation of subacute combined degeneration in pernicious anaemia

Jean M. Scott · The Lancet · 1981 · 269 citations

, , +17

Gas transport properties of polysulphones: 1. Role of symmetry of methyl group placement on bisphenol rings

J.S. McHattie, William J. Koros, D. R. Paul · Polymer · 1991 · 262 citations

, , +11

1–5 of 639

Authors

3.1K

  1. MG
    Mario Grifantini

    Università di Camerino, Italy

    4 publications · 115 citations

    4

    h-index

  2. LC
    Loredana Cappellacci

    Università di Camerino, Italy

    4 publications · 115 citations

    4

    h-index

  3. PF
    Palmarisa Franchetti

    Università di Camerino, Italy

    4 publications · 115 citations

    4

    h-index

  4. AA
    Abdelgawad A. Fahmi

    Cairo University, Egypt

    3 publications · 47 citations

    3

    h-index

  5. CD
    C. Dale Poulter

    University of Utah, United States

    3 publications · 94 citations

    3

    h-index

1–5 of 3.1K

Institutions

778

  1. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    57 publications

    1.5K citations

  2. National Institutes of Health

    Bethesda, United States

    10 h-index

    58 publications

    4.2K citations

  3. Washington University in St. Louis

    St Louis, United States

    7 h-index

    27 publications

    850 citations

  4. Chinese Academy of Sciences

    Beijing, China

    7 h-index

    21 publications

    732 citations

  5. University of Chicago

    Chicago, United States

    7 h-index

    16 publications

    1.2K citations

  6. The University of Osaka

    Osaka, Japan

    6 h-index

    17 publications

    527 citations

  7. Columbia University

    New York, United States

    6 h-index

    19 publications

    855 citations

  8. Cornell University

    Ithaca, United States

    5 h-index

    23 publications

    965 citations

1–8 of 778

Venues

  1. Journal of Medicinal Chemistry

    67 publications · 3.4K citations

    34

    h-index

  2. Journal of the American Chemical Society

    JACS · 23 publications · 1.2K citations

    18

    h-index

  3. Journal of Biological Chemistry

    JBC · 21 publications · 895 citations

    17

    h-index

  4. The Journal of Organic Chemistry

    JOC · 20 publications · 609 citations

    16

    h-index

  5. Biochemistry

    22 publications · 838 citations

    16

    h-index

1–5