Concepedia

Siegfried S. F. Leung

SS

15

Publications

1.8K

Citations

14

H-Index

2005

Active since

Affiliations

University of California, San Francisco(Current)

Yale University

University of California, Santa Cruz

Pfizer (United States)

Schrodinger (United States)

Siegfried S. F. Leung is an author at University of California, San Francisco specializing in biochemistry, medicine, and natural sciences.

Top concepts

MedicineBiochemistryNatural SciencesPharmacologyBiophysicsEngineeringMembrane TransportMedicinal ChemistryBiomolecular EngineeringDrug Discovery

Publications per year

2005–2017

15

Publications

15

Methyl Effects on Protein–Ligand Binding

Cheryl S. Leung, Siegfried S. F. Leung, Julian Tirado‐Rives et al. · Journal of Medicinal Chemistry · 2012 · 385 citations

On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds

Tina R. White, Chad M. Renzelman, Arthur C Rand et al. · Nature Chemical Biology · 2011 · 373 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +7

Cell-Permeable Cyclic Peptides from Synthetic Libraries Inspired by Natural Products

William M. Hewitt, Siegfried S. F. Leung, Cameron R. Pye et al. · Journal of the American Chemical Society · 2014 · 210 citations

Engineering, Peptide Engineering, Protein Folding +16

Structural Characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei Bound to the Antifungal Drugs Posaconazole and Fluconazole

Chiung-Kuang Chen, Siegfried S. F. Leung, Christophe Guilbert et al. · PLoS neglected tropical diseases · 2010 · 132 citations · Full text

Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance

Arthur C Rand, Siegfried S. F. Leung, Heather Eng et al. · MedChemComm · 2012 · 131 citations

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