Journal of Biological Chemistry · 2020 · 81 citations · 41 references
Life SciencesGeneticsMolecular BiologyEpigeneticsGene ExpressionGene FunctionDna MethylationTransfer Rna BiochemistryTransfer Rna FunctionDna Methylation ModulationDna MethyltransferasesEpigenetic RegulationTen-eleven Translocation EnzymesTet EnzymesTransfer Rna (Trna) ChemistryTrna Modification Effects
C oxidation in tRNA promotes translation in vitro. These results suggest TET2 may influence translation through impacting tRNA methylation and reveal an unexpected role for TET enzymes in regulating multiple nodes of the central dogma.
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