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Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO)

Shulei Pan, Qiusheng Wang, Yanlin Wang, Chenyu Tian, Tianqi Wang, Luyi Huang, Jinshan Nan, Linli Li, Shengyong Yang

European Journal of Medicinal Chemistry · 2020 · 34 citations · 72 references

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72

Ferrozine---a new spectrophotometric reagent for iron

Lawrence L. Stookey · Analytical Chemistry · 1970 · 4.7K citations

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New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

Jonathan B. Baell, Georgina A. Holloway · Journal of Medicinal Chemistry · 2010 · 3.9K citations

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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

Catherine Uyttenhove, Luc Pilotte, Ivan Théate et al. · Nature Medicine · 2003 · 2.3K citations

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Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

Luc Pilotte, Pierre Larrieu, Vincent Stroobant et al. · Proceedings of the National Academy of Sciences · 2012 · 570 citations · Full text

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INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology

Eddy W. Yue, Richard Sparks, Padmaja Polam et al. · ACS Medicinal Chemistry Letters · 2017 · 296 citations · Full text

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