Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

Ana P. Gomes, Nathan L. Price, Alvin J. Y. Ling et al. · Cell · 2013 · 1.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

SIRT1, an Antiinflammatory and Antiaging Protein, Is Decreased in Lungs of Patients with Chronic Obstructive Pulmonary Disease

R. Saravanan, Se‐Ran Yang, Vuokko L. Kinnula et al. · American Journal of Respiratory and Critical Care Medicine · 2008 · 520 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-κB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging

Se‐Ran Yang, Jessica Wright, Mark R. Bauter et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2006 · 390 citations

Life Sciences, Immunology, Molecular Biology +17

Regulation of FOXOs and p53 by SIRT1 Modulators under Oxidative Stress

Yusuke S. Hori, Atsushi Kuno, Ryusuke Hosoda et al. · PLoS ONE · 2013 · 353 citations · Full text

Life Sciences, Cell Biology, Oncology +17

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

Hongwei Yao, Sangwoon Chung, Jae‐Woong Hwang et al. · Journal of Clinical Investigation · 2012 · 351 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17