Ana P. Gomes

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

Ana P. Gomes, Nathan L. Price, Alvin J. Y. Ling et al. · Cell · 2013 · 1.4K citations · Full text

Mitochondrial Function, Longevity, Physiology +4

Metformin improves healthspan and lifespan in mice

Alejandro Martín‐Montalvo, Evi M. Mercken, Sarah J. Mitchell et al. · Nature Communications · 2013 · 1.4K citations · Full text

Lifespan Extension, Longevity, Medicine +4

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

Angela Hafner, Jing Dai, Ana P. Gomes et al. · Aging · 2010 · 533 citations · Full text

Cardiac Muscle, Heart Failure, Sirt3-mediated Deacetylation +18

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers

Edouard Mullarky, Natasha C. Lucki, Reza Beheshti Zavareh et al. · Proceedings of the National Academy of Sciences · 2016 · 331 citations · Full text

Engineering, Aldo-keto Reductase, Small Molecule Inhibitor +20

SRT1720 improves survival and healthspan of obese mice

Robin K. Minor, Joseph A. Baur, Ana P. Gomes et al. · Scientific Reports · 2011 · 287 citations · Full text