Alejandro Martín‐Montalvo

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

Nathan L. Price, Ana P. Gomes, Alvin J. Y. Ling et al. · Cell Metabolism · 2012 · 1.5K citations · Full text

Reductive Stress, Biochemistry, Mitochondrial Function +8

Metformin improves healthspan and lifespan in mice

Alejandro Martín‐Montalvo, Evi M. Mercken, Sarah J. Mitchell et al. · Nature Communications · 2013 · 1.4K citations · Full text

Lifespan Extension, Longevity, Medicine +4

Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans

Jaime Guevara‐Aguirre, Priya Balasubramanian, Marco Guevara‐Aguirre et al. · Science Translational Medicine · 2011 · 731 citations · Full text

Aging, Pathology, Cell Death +18

The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance

Changhan Lee, Jennifer Zeng, Brian G. Drew et al. · Cell Metabolism · 2015 · 698 citations · Full text

Obesity, Metabolic Syndrome, Insulin Resistance +14

Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

Changhan Lee, Lizzia Raffaghello, Sebastian Brandhorst et al. · Science Translational Medicine · 2012 · 692 citations · Full text

Cell Death, Metronomic Chemotherapy, Yeast Cells +18