Reza Beheshti Zavareh

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers

Edouard Mullarky, Natasha C. Lucki, Reza Beheshti Zavareh et al. · Proceedings of the National Academy of Sciences · 2016 · 331 citations · Full text

Engineering, Aldo-keto Reductase, Small Molecule Inhibitor +20

The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma

G. Wei Xu, Mohsin Ali, Tabitha E. Wood et al. · Blood · 2010 · 167 citations · Full text

The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma

Paul A. Spagnuolo, Jiayi Hu, Rose Hurren et al. · Blood · 2010 · 147 citations · Full text

JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma

Jaroslav Žák, Isaraphorn Pratumchai, Brett S. Marro et al. · Science · 2024 · 128 citations · Full text

Lymphoid Neoplasia, Hodgkin Lymphoma, Cancer Immunosurveillance +12

Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation

Craig D. Simpson, Imtiaz A. Mawji, Kika Anyiwe et al. · Cancer Research · 2009 · 103 citations