Nature Cell Biology · 2019 · 128 citations · 48 references
Life SciencesCancer BiologyMolecular BiologyCell SignalingMolecular OncologySignal TransductionCancer Cell SignalingCancer ProgressionGrowth Factor SignalingProtein Kinase CascadesTumor PromotionTumor Suppressor GenesGrowth Factor Receptor ActivationGrowth Factor Receptor ComplexesProtein Kinase B Signaling
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Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
David A. Barbie, Pablo Tamayo, Jesse S. Boehm et al. · Nature · 2009 · 4.2K citations · Full text
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
Chih‐Hao Chang, Jing Qiu, David O’Sullivan et al. · Cell · 2015 · 3.2K citations · Full text
Medicine, Cancer Biology, Oncology +16
Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma
Andrew T. Parsa, James S. Waldron, Amith Panner et al. · Nature Medicine · 2006 · 1.4K citations
Medicine, Cancer Biology, Oncology +14
Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors
Esra A. Akbay, Shohei Koyama, Julián Carretero et al. · Cancer Discovery · 2013 · 1.2K citations · Full text
Medicine, Immunology, Oncology +17
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
Leisa Johnson, Kim L. Mercer, Doron C. Greenbaum et al. · Nature · 2001 · 1.2K citations