Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis

Chun‐Jung Ko, Cheng-Chung Huang, Hsin-Ying Lin, +8

Cancer Research

Matriptase ActivationEndocrine-related CancerMedicineTumor GrowthHormonal Receptor +11

TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis

Lele Zhu, Yanchuan Li, Xiaoping Xie, +8

Nature Cell Biology

Tumor BiologySignal TransductionSignaling PathwayGrowth FactorMedicine +8

Prediction of microvascular invasion of hepatocellular carcinoma by pre-operative CT imaging

C-T Chou, R-C Chen, Chung‐Wei Lee, +3

British Journal of Radiology

HAI-2 suppresses the invasive growth and metastasis of prostate cancer through regulation of matriptase

C-H Tsai, C-H Teng, Y-T Tu, +11

Oncogene

UrologyInvasive GrowthMedicineCancer GrowthTumor Suppressor +5

Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination

Lingyun Zhang, Chun‐Jung Ko, Yanchuan Li, +8

Cell Reports

Innate Immune SystemImmunologyImmune RegulationCell DeathInnate Immunity +19

Proteomic analysis of osteoarthritic chondrocyte reveals the hyaluronic acid-regulated proteins involved in chondroprotective effect under oxidative stress

Chia-Jung Yu, Chun‐Jung Ko, Chang‐Hsun Hsieh, +4

Journal of Proteomics

Curcumin-Targeting Pericellular Serine Protease Matriptase Role in Suppression of Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis

Tai-Shan Cheng, Wen‐Chi Chen, Y. Lin, +9

Cancer Prevention Research

Matriptase ActivationChemoprevention StrategyMedicineTumor GrowthCancer Growth +11

DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis

Yanchuan Li, Xiaoping Xie, Zuliang Jie, +10

Blood

Inhibition of cyclooxygenase-2-mediated matriptase activation contributes to the suppression of prostate cancer cell motility and metastasis

Chun‐Jung Ko, S-W Lan, Y-C Lu, +12

Oncogene

UrologyOncologyMedicineAnti-cancer AgentCyclooxygenase-2-mediated Matriptase Activation +4

Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis

Chun‐Jung Ko, Ting-Wei Hsu, Shang‐Ru Wu, +11

Oncogene

MedicineReceptor Tyrosine KinaseAnti-cancer AgentProstatic DiseasePharmacology +3