Lele Zhu

C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection

Lele Zhu, Xue Qiang Zhao, Changying Jiang et al. · Immunity · 2013 · 330 citations · Full text

Dectin-2 Form, Pathogenesis, Immunology +7

CARD9 mediates Dectin-1–induced ERK activation by linking Ras-GRF1 to H-Ras for antifungal immunity

Xin‐Ming Jia, Bing Tang, Lele Zhu et al. · The Journal of Experimental Medicine · 2014 · 139 citations · Full text

Microbial Pathogens, Innate Immune System, Immune Regulation +21

TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis

Lele Zhu, Yanchuan Li, Xiaoping Xie et al. · Nature Cell Biology · 2019 · 122 citations · Full text

Tumor Biology, Signal Transduction, Signaling Pathway +10

C-type Lectin Receptor Dectin-3 Mediates Trehalose 6,6′-Dimycolate (TDM)-induced Mincle Expression through CARD9/Bcl10/MALT1-dependent Nuclear Factor (NF)-κB Activation

Xue Qiang Zhao, Lele Zhu, Qing Chang et al. · Journal of Biological Chemistry · 2014 · 114 citations · Full text

Transcriptional Regulation, Signal Transduction, Mincle Expression +15

NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity

Meidi Gu, Xiaofei Zhou, Jee Hyung Sohn et al. · Nature Immunology · 2021 · 106 citations · Full text

Nf-κb-inducing Kinase, Cancer Immunosurveillance, Immune Cell Development +9