Shohei Koyama

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

Shohei Koyama, Esra A. Akbay, Yvonne Y. Li et al. · Nature Communications · 2016 · 1.5K citations · Full text

Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors

Esra A. Akbay, Shohei Koyama, Julián Carretero et al. · Cancer Discovery · 2013 · 1.2K citations · Full text

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Shogo Kumagai, Shohei Koyama, Kota Itahashi et al. · Cancer Cell · 2022 · 752 citations

Cancer Immunosurveillance, Pd-1 Expression, Medicine +11

Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors

Pakawat Chongsathidkiet, Christina Jackson, Shohei Koyama et al. · Nature Medicine · 2018 · 641 citations · Full text

Neuro-oncology, Other Intracranial Tumors, Cell Therapy +11

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

Ken J. Ishii, Tatsukata Kawagoe, Shohei Koyama et al. · Nature · 2008 · 615 citations

Systems Biology, Signal Transduction, Adaptive Immune Responses +12