Concepedia

Biological plasticity rescues target activity in CRISPR knock outs

Arne H. Smits, Frederik Ziebell, Gérard Joberty, Nico Zinn, William F. Mueller, Sandra Clauder‐Münster, Dirk Eberhard, Maria Fälth Savitski, Paola Grandi, Petra Jakob,

Nature Methods · 2019 · 237 citations · 52 references

DOI

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References

52

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love, Wolfgang Huber, Simon Anders · Genome biology · 2014 · 100.5K citations · Full text

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STAR: ultrafast universal RNA-seq aligner

Alexander Dobin, Carrie Davis, Felix Schlesinger et al. · Bioinformatics · 2012 · 56.2K citations · Full text

, , +17

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

, , +17

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text

, , +15

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G. Doench, Nicolò Fusi, Meagan E. Sullender et al. · Nature Biotechnology · 2016 · 5K citations

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