Multiplexed genome engineering by Cas12a and CRISPR arrays encoded on single transcripts

Cutadapt removes adapter sequences from high-throughput sequencing reads

Marcel Martin · EMBnet journal · 2011 · 34K citations · Full text

Genetics, Genomics, High Throughput Sequencing +17

Analyzing real-time PCR data by the comparative CT method

Thomas D. Schmittgen, Kenneth J. Livak · Nature Protocols · 2008 · 26K citations

Computed Tomography, Image Analysis, Engineering +8

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Ben Langmead, Cole Trapnell, Mihai Pop et al. · Genome biology · 2009 · 22.5K citations · Full text

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

Lei S. Qi, Matthew H. Larson, Luke A. Gilbert et al. · Cell · 2013 · 5K citations · Full text

Off-target Effect, Engineering, Rna-guided Platform +9

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

Bernd Zetsche, Jonathan S. Gootenberg, Omar O. Abudayyeh et al. · Cell · 2015 · 4.7K citations · Full text

Rna Processing, Off-target Effect, Medicine +11