Concepedia

The AMPK–Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome

Seung Baek Lee, Sang‐Ah Han, Yingfang Fan, Li-Sha Guo, Khaled Aziz, Somaira Nowsheen, Sung Sun Kim, Seon‐Young Park, Qifeng Luo, Jin Ook Chung,

Nature Cell Biology · 2019 · 174 citations · 35 references

DOI

Concepts

References

35

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al. · Molecular Cell · 2008 · 3.8K citations · Full text

, , +15

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Carles Cantó, Zachary Gerhart‐Hines, Jérôme N. Feige et al. · Nature · 2009 · 3.2K citations · Full text

, , +15

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

Liming Sun, Huayi Wang, Zhigao Wang et al. · Cell · 2012 · 2.7K citations · Full text

, , +11

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

Young-Sik Cho, Sreerupa Challa, David Moquin et al. · Cell · 2009 · 2.4K citations · Full text

, , +15

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Hideki Shimura, Nobutaka Hattori, Shinichiro Kubo et al. · Nature Genetics · 2000 · 2K citations

, , +14