Somaira Nowsheen

PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy

Xinyi Tu, Bo Qin, Yong Zhang et al. · Molecular Cell · 2019 · 243 citations · Full text

Genome Instability, Molecular Biology, Can Be +7

The intersection between DNA damage response and cell death pathways.

Somaira Nowsheen, Eddy S. Yang · PubMed · 2012 · 211 citations

Dna Damage, Such Stress, Apoptosis +17

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

Jia Yu, Bo Qin, Ann M. Moyer et al. · Journal of Clinical Investigation · 2018 · 204 citations · Full text

Breast Oncology, Engineering, Cancer Biology +17

UFL1 promotes histone H4 ufmylation and ATM activation

Bo Qin, Jia Yu, Somaira Nowsheen et al. · Nature Communications · 2019 · 174 citations · Full text

The AMPK–Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome

Seung Baek Lee, Jung‐Jin Kim, Sang‐Ah Han et al. · Nature Cell Biology · 2019 · 167 citations

Signal Transduction, Ampk–parkin Axis, Signaling Pathway +10