Concepedia

Benzoyl indoles with metabolic stability as reversal agents for ABCG2-mediated multidrug resistance

Chao‐Yun Cai, Hong Zhai, Zi‐Ning Lei, Cai‐Ping Tan, Baoli Chen, Zhaoyi Du, Jing‐Quan Wang, Yunkai Zhang, Yi‐Jun Wang, Pranav Gupta,

European Journal of Medicinal Chemistry · 2019 · 35 citations · 32 references

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References

32

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

Timothy W. Synold, Isabelle Dussault, Barry M. Forman · Nature Medicine · 2001 · 834 citations

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Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

Arnold van Loevezijn, Jeany M Lakhai, Martin van der Valk et al. · PubMed · 2002 · 687 citations

, , +17

NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells

Mohamed Bentires‐Alj, Véronique Barbu, Marianne Fillet et al. · Oncogene · 2003 · 430 citations · Full text

, , +12

Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.

Yasuyuki Honjo, Christine A. Hrycyna, W Y Medina-Pérez et al. · PubMed · 2001 · 429 citations

, , +14

Structure of the human multidrug transporter ABCG2

Nicholas M. I. Taylor, Ioannis Manolaridis, Scott M. Jackson et al. · Nature · 2017 · 418 citations · Full text

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