Chao‐Yun Cai

Design and synthesis of novel xanthone-triazole derivatives as potential antidiabetic agents: α-Glucosidase inhibition and glucose uptake promotion

Gao‐Jie Ye, Tian Lan, Zhixin Huang et al. · European Journal of Medicinal Chemistry · 2019 · 116 citations · Full text

Medicinal Chemistry, Glucose Uptake Promotion, Medicine +7

Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters

Yingfang Fan, Wei Zhang, Leli Zeng et al. · Cancer Letters · 2018 · 111 citations · Full text

Multidrug Resistance, Cancer Biology, Abcg2 Transporters +18

Hsa-miR-3178/RhoB/PI3K/Akt, a novel signaling pathway regulates ABC transporters to reverse gemcitabine resistance in pancreatic cancer

Jianyou Gu, Wenjie Huang, Xianxing Wang et al. · Molecular Cancer · 2022 · 107 citations · Full text

Selonsertib (GS-4997), an ASK1 inhibitor, antagonizes multidrug resistance in ABCB1- and ABCG2-overexpressing cancer cells

Ning Ji, Yuqi Yang, Chao‐Yun Cai et al. · Cancer Letters · 2018 · 105 citations · Full text

Abcg2-overexpressing Cancer Cells, Oncology, Medicine +9

Analogues of xanthones——Chalcones and bis-chalcones as α-glucosidase inhibitors and anti-diabetes candidates

Chao‐Yun Cai, Li Rao, Yong Rao et al. · European Journal of Medicinal Chemistry · 2017 · 96 citations

Medicinal Chemistry, α-Glucosidase Inhibitors, Biochemistry +6