Structure of the human multidrug transporter ABCG2

Nicholas M. I. Taylor, Ioannis Manolaridis, Scott M. Jackson, +3

Nature

Molecular PharmacologyMolecular PhysiologyBiochemistryMedicineMembrane Transport +7

Structural basis of small-molecule inhibition of human multidrug transporter ABCG2

Scott M. Jackson, Ioannis Manolaridis, Julia Kowal, +11

Nature Structural & Molecular Biology

Molecular PharmacologyBiochemistryG Protein-coupled ReceptorMedicineNatural Sciences +7

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

Ioannis Manolaridis, Scott M. Jackson, Nicholas M. I. Taylor, +3

Nature

Cryo-em StructuresHuman Abcg2 MutantMolecular BiologyProtein PhosphorylationSubstrate-bound States +5

Mechanism of farnesylated CAAX protein processing by the intramembrane protease Rce1

Ioannis Manolaridis, Kiran Kulkarni, Roger B. Dodd, +9

Nature

Intramembrane Protease Rce1Protein SecretionProtein FunctionProtein AssemblyBiochemistry +6

Structure of the C-Terminal Domain of Human La Protein Reveals a Novel RNA Recognition Motif Coupled to a Helical Nuclear Retention Element

Amanda J. Jacks, Jeffrey J. Babon, Geoff Kelly, +4

Structure

ChromatinEngineeringRna Structure PredictionRna BiologyMolecular Biology +7

Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2

Julia Kowal, Dongchun Ni, Scott M. Jackson, +3

Journal of Molecular Biology

Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism

Qin Yu, Dongchun Ni, Julia Kowal, +4

Nature Communications

Papain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular Substrates

J.A. Wojdyla, Ioannis Manolaridis, Puck B. van Kasteren, +4

Journal of Virology

Mechanism of Isoprenylcysteine Carboxyl Methylation from the Crystal Structure of the Integral Membrane Methyltransferase ICMT

Jing Yang, Kiran Kulkarni, Ioannis Manolaridis, +4

Molecular Cell

Crystal StructureBiochemistryNatural SciencesIsoprenylcysteine Carboxyl MethylationEpigenomics +6

Structure of the C-terminal domain of nsp4 from feline coronavirus

Ioannis Manolaridis, J.A. Wojdyla, Santosh Panjikar, +6

Acta Crystallographica Section D Biological Crystallography

Virus StructurePrototypical Crystal StructureViral ReplicationLarge Coronavirus GenomeBiochemistry +12