Julia Kowal

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

Amer Alam, Julia Kowal, Eugenia V. Broude et al. · Science · 2019 · 453 citations · Full text

Proteinlipid Interaction, Drug Target, Glycobiology +17

Structure of the human multidrug transporter ABCG2

Nicholas M. I. Taylor, Ioannis Manolaridis, Scott M. Jackson et al. · Nature · 2017 · 409 citations · Full text

Molecular Pharmacology, Molecular Physiology, Biochemistry +9

Structural basis of small-molecule inhibition of human multidrug transporter ABCG2

Scott M. Jackson, Ioannis Manolaridis, Julia Kowal et al. · Nature Structural & Molecular Biology · 2018 · 329 citations · Full text

Molecular Pharmacology, Biochemistry, G Protein-coupled Receptor +9

Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1

Kamil Nosol, Ksenija Romane, Rossitza N. Irobalieva et al. · Proceedings of the National Academy of Sciences · 2020 · 239 citations · Full text

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

Ioannis Manolaridis, Scott M. Jackson, Nicholas M. I. Taylor et al. · Nature · 2018 · 230 citations · Full text

Cryo-em Structures, Human Abcg2 Mutant, Molecular Biology +7