Role of tea polyphenols in delaying hyperglycemia-induced senescence in human glomerular mesangial cells via miR-126/Akt–p53–p21 pathways

Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy

Daniela Verzola, Maria Teresa Gandolfo, Gianfranco Gaetani et al. · American Journal of Physiology-Renal Physiology · 2008 · 289 citations

Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1

Jingli Cao, B. Zhang, Qing Zhou et al. · Journal of Molecular and Cellular Cardiology · 2012 · 249 citations

Endothelial Progenitor Cells, Functional Properties, Functional Genomics +13

Hyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy

Kento Kitada, Daisuke Nakano, Hiroyuki Ohsaki et al. · Journal of Diabetes and its Complications · 2014 · 140 citations

Medicine, Physiology, Diabetes +9

Intermittent High Glucose Implements Stress-Induced Senescence in Human Vascular Endothelial Cells: Role of Superoxide Production by NADPH Oxidase

Morihiko Maeda, Toshio Hayashi, Natsumi Mizuno et al. · PLoS ONE · 2015 · 111 citations · Full text

Constant High Glucose, Aging, Anti-aging +25

NADPH oxidase NOX1 is involved in activation of protein kinase C and premature senescence in early stage diabetic kidney

Kai Zhu, Tomoko Kakehi, Misaki Matsumoto et al. · Free Radical Biology and Medicine · 2015 · 76 citations

Protein Kinase C, Biochemistry, Medicine +12