Hiroyuki Ohsaki

Hyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy

Kento Kitada, Daisuke Nakano, Hiroyuki Ohsaki et al. · Journal of Diabetes and its Complications · 2014 · 145 citations

Medicine, Cell Biology, Nephrology +17

A neutrophil elastase inhibitor (ONO‐5046) reduces neurologic damage after spinal cord injury in rats

Takeharu Tonai, Keiichiro Shiba, Yutaka Taketani et al. · Journal of Neurochemistry · 2001 · 87 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Aldosterone/Mineralocorticoid Receptor Stimulation Induces Cellular Senescence in the Kidney

Yu-Yan Fan, Masakazu Kohno, Hirofumi Hitomi et al. · Endocrinology · 2010 · 54 citations · Full text

Medicine, Endocrinology, Pharmacology +16

(Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signalling pathway despite constitutive pathway component mutations

Juan Wang, Yuki Shibayama, Anqi Zhang et al. · British Journal of Cancer · 2018 · 51 citations · Full text

Medicine, Cancer Biology, Molecular Biology +16

The cyclin-dependent kinase inhibitor p21 is essential for the beneficial effects of renal ischemic preconditioning on renal ischemia/reperfusion injury in mice

Satoshi Nishioka, Daisuke Nakano, Kento Kitada et al. · Kidney International · 2013 · 50 citations · Full text

Medicine, Molecular Medicine, Nephrology +14