Concepedia

Hyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy

Kento Kitada, Daisuke Nakano, Hiroyuki Ohsaki, Hirofumi Hitomi, Tohru Minamino, Junichi Yatabe, Robin A. Felder, Hirohito Mori, Tsutomu Masaki, Hiroyuki Kobori,

Journal of Diabetes and its Complications · 2014 · 145 citations · 32 references

DOI

Concepts

References

32

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

Shin Yoshimoto, Tze Mun Loo, Koji Atarashi et al. · Nature · 2013 · 2.2K citations

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Endothelial Cell Senescence in Human Atherosclerosis

Tohru Minamino, Hideaki Miyauchi, Toshihiko Yoshida et al. · Circulation · 2002 · 1K citations

, , +17

The sodium/glucose cotransport family SLC5

Ernest M. Wright, Eric Turk · Pflügers Archiv - European Journal of Physiology · 2004 · 534 citations · Full text

, , +6

Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus

Volker Vallon, Michael Rose, Maria Gerasimova et al. · American Journal of Physiology-Renal Physiology · 2012 · 369 citations

, , +17

Repair of injured proximal tubule does not involve specialized progenitors

Benjamin D. Humphreys, Suzanne Czerniak, Derek P. DiRocco et al. · Proceedings of the National Academy of Sciences · 2011 · 367 citations · Full text

, , +15