Concepedia

Proximal Tubular Dysfunction

Proximal Tubular Dysfunction is a renal pathophysiological condition characterized by impaired reabsorptive and secretory functions of the proximal convoluted tubule, primarily resulting from structural damage or cellular toxicity that disrupts ion, nutrient, and solute transport in the nephron.

1.8K

Publications

93.1K

Citations

8.7K

Authors

1.8K

Institutions

Publications per year

2017–2026

371

Parents

Publications

1.8K

Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury

Won Kon Han, Véronique Bailly, Rekha Abichandani et al. · Kidney International · 2002 · 1.9K citations · Full text

, , +13

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

Shinji Kume, Takashi Uzu, Kihachiro Horiike et al. · Journal of Clinical Investigation · 2010 · 632 citations · Full text

, , +17

Quercetin alleviates acute kidney injury by inhibiting ferroptosis

Yue Wang, Fei Quan, Qiuhua Cao et al. · Journal of Advanced Research · 2020 · 603 citations · Full text

, , +15

Ischemic damage and repair in the rat proximal tubule: Differences among the S1, S2, and S3 segments

Manjeri A. Venkatachalam, David B. Bernard, J. Donohoe et al. · Kidney International · 1978 · 501 citations

, , +15

Autophagy in proximal tubules protects against acute kidney injury

Man Jiang, Qingqing Wei, Guie Dong et al. · Kidney International · 2012 · 470 citations · Full text

, , +14

1–5 of 1.8K

Authors

8.7K

  1. JR
    Julie R. Ingelfinger

    Massachusetts General Hospital, United States

    20 publications · 1.2K citations

    18

    h-index

  2. JS
    John S.D. Chan

    Hôpital Maisonneuve-Rosemont, Canada

    17 publications · 877 citations

    15

    h-index

  3. RA
    Richard A. Zager

    University of Washington, United States

    16 publications · 826 citations

    15

    h-index

  4. CA
    Carol A. Pollock

    The University of Sydney, Australia

    14 publications · 853 citations

    14

    h-index

  5. JG
    János G. Filep

    Hôpital Maisonneuve-Rosemont, Canada

    14 publications · 786 citations

    13

    h-index

1–5 of 8.7K

Institutions

1.8K

  1. Harvard University

    Cambridge, United States

    32 h-index

    131 publications

    21.3K citations

  2. Massachusetts General Hospital

    Boston, United States

    25 h-index

    74 publications

    7.9K citations

  3. Inserm

    Paris, France

    25 h-index

    148 publications

    10.8K citations

  4. University College London

    London, United Kingdom

    21 h-index

    71 publications

    6.6K citations

  5. Aarhus University

    Aarhus, Denmark

    20 h-index

    70 publications

    2.9K citations

  6. Fred Hutch Cancer Center

    Seattle, United States

    20 h-index

    51 publications

    2.4K citations

  7. University of Washington

    Seattle, United States

    20 h-index

    67 publications

    3.5K citations

  8. National Institutes of Health

    Bethesda, United States

    19 h-index

    72 publications

    5.3K citations

1–8 of 1.8K

Venues

  1. Kidney International

    120 publications · 12.5K citations

    57

    h-index

  2. American Journal of Physiology-Renal Physiology

    105 publications · 5.9K citations

    50

    h-index

  3. Journal of the American Society of Nephrology

    72 publications · 6.4K citations

    46

    h-index

  4. PubMed

    Repository · 125 publications · 4.8K citations

    38

    h-index

  5. Nephrology Dialysis Transplantation

    NDT · 41 publications · 1.8K citations

    25

    h-index

1–5