Intermittent High Glucose Implements Stress-Induced Senescence in Human Vascular Endothelial Cells: Role of Superoxide Production by NADPH Oxidase

Morihiko Maeda, Toshio Hayashi, Natsumi Mizuno, +2

PLoS ONE

Constant High GlucoseAgingAnti-agingNadph OxidaseLipid Peroxidation +23

Induction of Cardiac Fibrosis by β-Blocker in G Protein-independent and G Protein-coupled Receptor Kinase 5/β-Arrestin2-dependent Signaling Pathways

Michio Nakaya, Satsuki Chikura, Kenji Watari, +9

Journal of Biological Chemistry

Cardiac MuscleG Protein-independentCardiovascular PharmacologyPharmacotherapyMolecular Pharmacology +17

Cardiac fibroblasts: contributory role in septic cardiac dysfunction

Kengo Tomita, Mitchinori Takashina, Natsumi Mizuno, +5

Journal of Surgical Research

InflammationCardiac MuscleCardiomyopathyHeart FailureCardiovascular Disease +7

Roles of ROS and PKC-βII in ionizing radiation-induced eNOS activation in human vascular endothelial cells

Kimimasa Sakata, Takashi Kondo, Natsumi Mizuno, +7

Vascular Pharmacology

Radiation MedicineMolecular PhysiologySignal TransductionRadiation BiologyEndothelial Dysfunction +7

EGFR transactivation is involved in TNF-α-induced expression of thymic stromal lymphopoietin in human keratinocyte cell line

Ryosuke Segawa, Kenichi Shigeeda, Takahiro Hatayama, +5

Journal of Dermatological Science

Skin DevelopmentLymphocyte DevelopmentCutaneous BiologyImmunologyImmune Regulation +9

Hypoxia inhibits TNF-α-induced TSLP expression in keratinocytes

Naoyuki Tashiro, Ryosuke Segawa, Ryozo Tobita, +4

PLoS ONE

Inflammatory Lung DiseaseImmune RegulationImmunologyCell DeathSkin Allergy +21

Nickel ions bind to HSP90β and enhance HIF-1α-mediated IL-8 expression

Sanki Asakawa, Ryo Onodera, Koji Kasai, +8

Toxicology

InflammationSignal TransductionMetalloproteinImmunologyMolecular Biology +6

Identification of a cell line producing high levels of TSLP: Advantages for screening of anti-allergic drugs

Ryosuke Segawa, Saori Yamashita, Natsumi Mizuno, +6

Journal of Immunological Methods

Signal TransductionAllergyAutoimmune DiseaseAllergy MedicineMedicine +9

Zinc ions have a potential to attenuate both Ni ion uptake and Ni ion-induced inflammation

Ryo Onodera, Sanki Asakawa, Ryosuke Segawa, +4

Scientific Reports

Inhibitory effects of nicotine derived from cigarette smoke on thymic stromal lymphopoietin production in epidermal keratinocytes

Jiangxu Dong, Ryosuke Segawa, Natsumi Mizuno, +2

Cellular Immunology

Inhibitory EffectsImmunologyEpidermal KeratinocytesDermatologyCigarette Smoke +2