Concepedia

A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9

Basudeb Maji, Soumyashree A. Gangopadhyay, Miseon Lee, Meng‐Chao Shi, Peng Wu, Robert Heler, Beverly Mok, Donghyun Lim, Sachini U. Siriwardena, Bishwajit Paul,

Cell · 2019 · 192 citations · 34 references

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References

34

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

, , +17

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

, , +16

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor, Y. Bill Kim, Michael S. Packer et al. · Nature · 2016 · 5.4K citations · Full text

, , +9

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

Haoyi Wang, Hui Yang, Chikdu Shivalila et al. · Cell · 2013 · 3.6K citations · Full text

, , +14

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Yanfang Fu, Jennifer A Foden, Cyd Khayter et al. · Nature Biotechnology · 2013 · 3.3K citations · Full text

, , +16