Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 17K citations · Full text

Iron Deficiency, Nonapoptotic Cell Death, Metalloprotein +9

Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell · 2014 · 7.1K citations · Full text

Tumor Biology, Medicine, Apoptosis +5

Principles of nanoparticle design for overcoming biological barriers to drug delivery

Elvin Blanco, Haifa Shen, Mauro Ferrari · Nature Biotechnology · 2015 · 6.4K citations · Full text

Nanoparticles, Nanomedicine, Biological Barriers +6

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, Bettina Proneth, Yulia Y. Tyurina et al. · Nature Chemical Biology · 2016 · 3.8K citations · Full text

Proteinlipid Interaction, Biochemistry, Natural Sciences +4

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Valerian E. Kagan, Gaowei Mao, Feng Qu et al. · Nature Chemical Biology · 2016 · 2.7K citations · Full text

Adrenal Gland, Oxysterol, Biochemistry +9