ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, Bettina Proneth, Yulia Y. Tyurina, +18

Nature Chemical Biology

Proteinlipid InteractionBiochemistryNatural SciencesFerroptosis SensitivityLipid Movement +2

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

José Pedro Friedmann Angeli, Manuela Schneider, Bettina Proneth, +26

Nature Cell Biology

GlomerulonephritisUrologyRenal FunctionMedicineRenal Failure +10

FSP1 is a glutathione-independent ferroptosis suppressor

Sebastian Doll, Florêncio Porto Freitas, Ron Shah, +29

Nature

Redox SignalingSignal TransductionBiochemistryMedicineNatural Sciences +5

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Valerian E. Kagan, Gaowei Mao, Feng Qu, +23

Nature Chemical Biology

Adrenal GlandOxysterolBiochemistryPhysiologyCytoskeleton +7

A non-canonical vitamin K cycle is a potent ferroptosis suppressor

Eikan Mishima, Junya Ito, Zijun Wu, +24

Nature

Phase separation of FSP1 promotes ferroptosis

Toshitaka Nakamura, Clara Hipp, André Mourão, +10

Nature

Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

Wulf Tonnus, Claudia Meyer, Christian Steinebach, +29

Nature Communications

Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines

Jiashuo Zheng, Mami Sato, Eikan Mishima, +3

Cell Death and Disease

Pharmacological Characterization of 40 Human Melanocortin-4 Receptor Polymorphisms with the Endogenous Proopiomelanocortin-Derived Agonists and the Agouti-Related Protein (AGRP) Antagonist^,

Zhimin Xiang, Sally A. Litherland, Nicholas B. Sorensen, +5

Biochemistry

Activation of lysosomal iron triggers ferroptosis in cancer

Tatiana Cañeque, Leeroy Baron, Sebastian Müller, +43

Nature