Valerian E. Kagan

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, Bettina Proneth, Yulia Y. Tyurina et al. · Nature Chemical Biology · 2016 · 4.1K citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

José Pedro Friedmann Angeli, Manuela Schneider, Bettina Proneth et al. · Nature Cell Biology · 2014 · 3.6K citations

Medicine, Nephrology, Pathobiology +10

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Valerian E. Kagan, Gaowei Mao, Feng Qu et al. · Nature Chemical Biology · 2016 · 2.8K citations · Full text

Life Sciences, Biochemistry, Cell Biology +7

Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice

Anna A. Shvedova, Elena R. Kisin, Robert R. Mercer et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2005 · 1.3K citations

Veterinary Medicine, Immunology, Pathobiology +17

Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

Valerian E. Kagan, Vladimir A. Tyurin, Jianfei Jiang et al. · Nature Chemical Biology · 2005 · 1.2K citations

Life Sciences, Biochemistry, Cell Biology +13