Concepedia

Cell-cycle Dysregulation

Cell-Cycle Dysregulation is a molecular pathological process characterized by the disruption of the tightly regulated sequence of events governing cell division, resulting in uncontrolled proliferation due to aberrant activity of cyclins, cyclin-dependent kinases, and checkpoint control mechanisms.

9.5K

Publications

594.4K

Citations

53.6K

Authors

5.5K

Institutions

Publications per year

2017–2026

2.4K

Variants

Cell Cycle Dysregulation

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Publications

9.5K

p21 is a universal inhibitor of cyclin kinases

Yue Xiong, Gregory J. Hannon, Hui Zhang et al. · Nature · 1993 · 3.4K citations

, , +14

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Michael B. Kastan, Qimin Zhan, Wafik S. El‐Deiry et al. · Cell · 1992 · 3.1K citations

, , +12

Transcriptional Profiling of the Human Monocyte-to-Macrophage Differentiation and Polarization: New Molecules and Patterns of Gene Expression

Fernando O. Martínez, Siamon Gordon, Massimo Locati et al. · The Journal of Immunology · 2006 · 2.3K citations · Full text

, , +17

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

Kornélia Polyák, Mong-Hong Lee, Hediye Erdjument‐Bromage et al. · Cell · 1994 · 2.1K citations

, , +15

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

Pumin Zhang, J. Wade Harper, Stephen J. Elledge et al. · Cell · 1995 · 2.1K citations · Full text

, , +11

1–5 of 9.5K

Authors

53.6K

  1. KK
    Khandan Keyomarsi

    The University of Texas MD Anderson Cancer Center, United States

    34 publications · 3.5K citations

    27

    h-index

  2. GL
    Göran Landberg

    Lund University, Sweden

    27 publications · 1.9K citations

    22

    h-index

  3. RG
    Richard G. Pestell

    Thomas Jefferson University, United States

    22 publications · 2.3K citations

    22

    h-index

  4. JB
    Jiří Bártek

    Danish Cancer Society, Denmark

    24 publications · 3.6K citations

    22

    h-index

  5. PS
    Piotr Siciński

    Dana-Farber Cancer Institute, United States

    22 publications · 6.5K citations

    20

    h-index

1–5 of 53.6K

Institutions

5.5K

  1. Harvard University

    Cambridge, United States

    95 h-index

    922 publications

    139.3K citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    77 h-index

    1.1K publications

    95.5K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    69 h-index

    644 publications

    98.2K citations

  4. National Cancer Institute

    Bethesda, United States

    60 h-index

    430 publications

    54.6K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    59 h-index

    229 publications

    69.6K citations

  6. Inserm

    Paris, France

    59 h-index

    725 publications

    54.1K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    53 h-index

    481 publications

    44.7K citations

  8. Memorial Sloan Kettering Cancer Center

    New York, United States

    52 h-index

    380 publications

    57.1K citations

1–8 of 5.5K

Venues

  1. PubMed

    Repository · 693 publications · 50.9K citations

    116

    h-index

  2. Cancer Research

    215 publications · 20.2K citations

    86

    h-index

  3. Journal of Biological Chemistry

    JBC · 262 publications · 21.7K citations

    84

    h-index

  4. Oncogene

    270 publications · 19.5K citations

    84

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 139 publications · 20.9K citations

    83

    h-index

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