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Directed Evolution of Canonical Loops and Their Swapping between Unrelated Serine Proteinase Inhibitors Disprove the Interscaffolding Additivity Model

Protein ChemistryProtein AssemblyProtein FoldingNatural SciencesMedicineDirected EvolutionProtein EvolutionMolecular BiologyInterscaffolding Additivity ModelProtein ModelingProtein EngineeringSystems BiologyCanonical LoopsMulti-protein AssemblyStructural Biology