Dávid Héja

Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2

Dávid Héja, Andrea Kocsis, József Dobó et al. · Proceedings of the National Academy of Sciences · 2012 · 246 citations · Full text

Protein Secretion, Glycobiology, Immunology +23

Design and testing of a humanized porcine donor for xenotransplantation

R. Anand, Jacob V. Layer, Dávid Héja et al. · Nature · 2023 · 235 citations · Full text

Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2

Dávid Héja, Veronika Harmat, Krisztián Fodor et al. · Journal of Biological Chemistry · 2012 · 84 citations · Full text

Dynamic regulation of B cell complement signaling is integral to germinal center responses

Arun Čumpelik, Dávid Héja, Yuan Hu et al. · Nature Immunology · 2021 · 81 citations · Full text

Dynamic Regulation, Complement System, Signal Transduction +10

Quantitative Characterization of the Activation Steps of Mannan-binding Lectin (MBL)-associated Serine Proteases (MASPs) Points to the Central Role of MASP-1 in the Initiation of the Complement Lectin Pathway

Márton Megyeri, Veronika Harmat, Balázs Major et al. · Journal of Biological Chemistry · 2013 · 70 citations · Full text

Complement System, Protein Function, Signal Transduction +14