Concepedia

Jacob V. Layer

JV

11

Publications

880

Citations

11

H-Index

2011

Active since

Affiliations

Harvard University(Current)

Broad Institute

Dana-Farber Cancer Institute

Genesis Foundation

Massachusetts General Hospital

Jacob V. Layer is an author at Harvard University specializing in medicine, genetics, and genomics.

Top concepts

Publications per year

2011–2023

11

Publications

11

Design and testing of a humanized porcine donor for xenotransplantation

R. Anand, Jacob V. Layer, Dávid Héja et al. · Nature · 2023 · 235 citations · Full text

Extensive germline genome engineering in pigs

Yanan Yue, Weihong Xu, Yinan Kan et al. · Nature Biomedical Engineering · 2020 · 158 citations

, , +10

Kidney transplantation from triple-knockout pigs expressing multiple human proteins in cynomolgus macaques

Dávid Ma, Takayuki Hirose, Grace Lassiter et al. · American Journal of Transplantation · 2021 · 135 citations · Full text

Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia

Shuo-Chieh Wu, Loretta S. Li, Nadja Kopp et al. · Cancer Cell · 2015 · 120 citations · Full text

, , +6

An “Exacerbate-reverse” Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick Type C Disease

Andrew B. Munkacsi, Fannie W. Chen, Matthew Brinkman et al. · Journal of Biological Chemistry · 2011 · 89 citations · Full text

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