Fannie W. Chen

Transmembrane Molecular Pump Activity of Niemann-Pick C1 Protein

Joanna P. Davies, Fannie W. Chen, Yiannis A. Ioannou · Science · 2000 · 320 citations

Proteinlipid Interaction, Protein Function, Npc1 Protein +12

Niemann–Pick C1 Is a Late Endosome-Resident Protein That Transiently Associates with Lysosomes and the Trans-Golgi Network

Maureen E. Higgins, Joanna P. Davies, Fannie W. Chen et al. · Molecular Genetics and Metabolism · 1999 · 260 citations

Protein Function, Niemann–pick C1, Medicine +11

Cyclodextrin Induces Calcium-Dependent Lysosomal Exocytosis

Fannie W. Chen, Chunlei Li, Yiannis A. Ioannou · PLoS ONE · 2010 · 113 citations · Full text

Molecular Biology, Cellular Physiology, Endocytic Pathway +18

An “Exacerbate-reverse” Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick Type C Disease

Andrew B. Munkacsi, Fannie W. Chen, Matthew Brinkman et al. · Journal of Biological Chemistry · 2011 · 89 citations · Full text

Endosomal lipid accumulation in NPC1 leads to inhibition of PKC, hypophosphorylation of vimentin and Rab9 entrapment

Marc Walter, Fannie W. Chen, Farshad Tamari et al. · Biology of the Cell · 2008 · 57 citations