High production of 4-hydroxyisoleucine in Corynebacterium glutamicum by multistep metabolic engineering

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

Life Sciences, Molecular Biology, Molecular Genetics +9

Determination of the fluxes in the central metabolism ofCorynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing

Achim Marx, Albert A. de Graaf, Wolfgang Wiechert et al. · Biotechnology and Bioengineering · 1996 · 406 citations

Life Sciences, Biochemistry, Microbiology +15

Pyruvate carboxylase is a major bottleneck for glutamate and lysine production by Corynebacterium glutamicum.

Petra Peters‐Wendisch, Bettina Schiel, Volker F. Wendisch et al. · PubMed · 2001 · 280 citations

Life Sciences, Microbiology, Molecular Biology +17

Amplified Expression of Fructose 1,6-Bisphosphatase in <i>Corynebacterium glutamicum</i> Increases In Vivo Flux through the Pentose Phosphate Pathway and Lysine Production on Different Carbon Sources

Judith Becker, Corinna Klopprogge, Oskar Zelder et al. · Applied and Environmental Microbiology · 2005 · 230 citations · Full text

Life Sciences, Biotechnology, Microbiology +17

Corynebacterial Protein Kinase G Controls 2-Oxoglutarate Dehydrogenase Activity via the Phosphorylation Status of the OdhI Protein

Axel Niebisch, Armin Kabus, Christian Schultz et al. · Journal of Biological Chemistry · 2006 · 220 citations · Full text

Life Sciences, Biochemistry, Microbiology +17