Albert A. de Graaf

Identification of a thiamin-dependent synthase in <i>Escherichia coli</i> required for the formation of the 1-deoxy- <scp>d</scp> -xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol

Georg A. Sprenger, Ulrich Schörken, Thomas Wiegert et al. · Proceedings of the National Academy of Sciences · 1997 · 461 citations · Full text

Life Sciences, Biochemistry, Microbiology +13

Determination of the fluxes in the central metabolism ofCorynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing

Achim Marx, Albert A. de Graaf, Wolfgang Wiechert et al. · Biotechnology and Bioengineering · 1996 · 406 citations

Life Sciences, Biochemistry, Microbiology +15

A Universal Framework for 13C Metabolic Flux Analysis

Wolfgang Wiechert, Michael Möllney, Albert A. de Graaf · Metabolic Engineering · 2001 · 356 citations

Life Sciences, Biochemistry, Cellular Metabolism +10

Bidirectional reaction steps in metabolic networks: III. Explicit solution and analysis of isotopomer labeling systems

Wolfgang Wiechert, Michael M�llney, Nichole Isermann et al. · Biotechnology and Bioengineering · 1999 · 269 citations

Life Sciences, Biochemistry, Cellular Metabolism +16

Bidirectional reaction steps in metabolic networks: I. Modeling and simulation of carbon isotope labeling experiments

Wolfgang Wiechert, Albert A. de Graaf · Biotechnology and Bioengineering · 1997 · 267 citations

Life Sciences, Biochemistry, Biological Systems Modeling +16