Concepedia

Rational Metabolic Engineering

Rational Metabolic Engineering is a systematic approach within metabolic engineering that relies on the deliberate design and targeted modification of metabolic pathways based on comprehensive mechanistic understanding and predictive models to achieve specific biochemical production goals.

455

Publications

29.7K

Citations

2.2K

Authors

523

Institutions

Publications per year

2017–2026

242

Parents

Publications

455

Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol

Harry Yim, Robert J. Haselbeck, Wei Niu et al. · Nature Chemical Biology · 2011 · 1.1K citations

, , +16

Metabolic engineering of Escherichia coli for 1-butanol production

Shota Atsumi, Anthony F. Cann, Michael R. Connor et al. · Metabolic Engineering · 2007 · 837 citations

, , +16

From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine production

Judith Becker, Oskar Zelder, Stefan S. Hafner et al. · Metabolic Engineering · 2011 · 609 citations

, , +16

Metabolic engineering of <i>Escherichia coli</i> for the production of <scp>l</scp> -valine based on transcriptome analysis and <i>in silico</i> gene knockout simulation

Jin Hwan Park, Kwang Ho Lee, Tae Yong Kim et al. · Proceedings of the National Academy of Sciences · 2007 · 606 citations

, , +17

Improving lycopene production in Escherichia coli by engineering metabolic control

William R. Farmer, James C. Liao · Nature Biotechnology · 2000 · 529 citations

, , +16

1–5 of 455

Authors

2.2K

  1. SY
    Sang Yup Lee

    Korea Advanced Institute of Science and Technology, South Korea

    19 publications · 2.9K citations

    19

    h-index

  2. GS
    Gregory Stephanopoulos

    Massachusetts Institute of Technology, United States

    9 publications · 414 citations

    9

    h-index

  3. JC
    James C. Liao

    University of California, Los Angeles, United States

    8 publications · 2.1K citations

    8

    h-index

  4. DL
    Dehua Liu

    Tsinghua University, China

    7 publications · 341 citations

    7

    h-index

  5. JC
    Jian Chen

    Jiangnan University, China

    7 publications · 386 citations

    7

    h-index

1–5 of 2.2K

Institutions

523

  1. Korea Advanced Institute of Science and Technology

    Daejeon, South Korea

    23 h-index

    79 publications

    7.7K citations

  2. Jiangnan University

    Wuxi, China

    20 h-index

    158 publications

    6.4K citations

  3. Chinese Academy of Sciences

    Beijing, China

    18 h-index

    123 publications

    6K citations

  4. University of Chinese Academy of Sciences

    Beijing, China

    15 h-index

    34 publications

    1.6K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    12 h-index

    53 publications

    2.8K citations

  6. Zhejiang University

    Hangzhou, China

    12 h-index

    69 publications

    4.5K citations

  7. Technical University of Denmark

    Kongens Lyngby, Denmark

    12 h-index

    40 publications

    2.5K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    12 h-index

    32 publications

    1.5K citations

1–8 of 523

Venues

  1. Metabolic Engineering

    83 publications · 8.4K citations

    52

    h-index

  2. Applied Microbiology and Biotechnology

    26 publications · 1.3K citations

    23

    h-index

  3. Bioresource Technology

    29 publications · 1.1K citations

    22

    h-index

  4. Microbial Cell Factories

    19 publications · 878 citations

    17

    h-index

  5. Biotechnology and Bioengineering

    18 publications · 1.1K citations

    16

    h-index

1–5