Improving lycopene production in Escherichia coli by engineering metabolic control

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Improved single and multicopy lac-based cloning vectors for protein and operon fusions

Robert W. Simons, Fariba Houman, Nancy Kleckner · Gene · 1987 · 1.5K citations

Life Sciences, Biotechnology, Molecular Biology +13

Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector

Jens P. Fürste, Werner Pansegrau, Ronald Frank et al. · Gene · 1986 · 1K citations

Life Sciences, Molecular Biology, Molecular Genetics +15

Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli

Norihiko Misawa, Masaya Nakagawa, Kazuo Kobayashi et al. · Journal of Bacteriology · 1990 · 605 citations

Life Sciences, Biochemistry, Plant Biology +14

Identification of a thiamin-dependent synthase in <i>Escherichia coli</i> required for the formation of the 1-deoxy- <scp>d</scp> -xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol

Georg A. Sprenger, Ulrich Schörken, Thomas Wiegert et al. · Proceedings of the National Academy of Sciences · 1997 · 461 citations · Full text

Life Sciences, Biochemistry, Microbiology +13