Concepedia

Biosynthetic Pathway Optimization

Biosynthetic Pathway Optimization is a metabolic engineering strategy that systematically refines the enzymatic steps, regulatory elements, and flux distribution within a reconstructed or native metabolic pathway in microbial or plant systems to enhance the yield, specificity, or efficiency of target compound production.

271

Publications

19.6K

Citations

1.4K

Authors

376

Institutions

Publications per year

2017–2026

156

Parents

Publications

271

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in <i>Escherichia coli</i>

Parayil Kumaran Ajikumar, Wenhai Xiao, Keith E. J. Tyo et al. · Science · 2010 · 1.6K citations

, , +17

Improving lycopene production in Escherichia coli by engineering metabolic control

William R. Farmer, James C. Liao · Nature Biotechnology · 2000 · 529 citations

, , +16

Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli

Hal S. Alper, Yong‐Su Jin, Joel F. Moxley et al. · Metabolic Engineering · 2005 · 456 citations

, , +17

Expanding metabolism for biosynthesis of nonnatural alcohols

Kechun Zhang, M.R. Sawaya, David Eisenberg et al. · Proceedings of the National Academy of Sciences · 2008 · 418 citations · Full text

, , +17

Cyanobacterial conversion of carbon dioxide to 2,3-butanediol

John W. K. Oliver, Iara M.P. Machado, Hisanari Yoneda et al. · Proceedings of the National Academy of Sciences · 2013 · 388 citations · Full text

, , +17

1–5 of 271

Authors

1.4K

  1. QH
    Qiang Hua

    East China University of Science and Technology, China

    6 publications · 382 citations

    6

    h-index

  2. GD
    Guocheng Du

    Jiangnan University, China

    6 publications · 420 citations

    6

    h-index

  3. JZ
    Jingwen Zhou

    Jiangnan University, China

    6 publications · 530 citations

    6

    h-index

  4. JN
    Jens Nielsen

    Chalmers University of Technology, Sweden

    5 publications · 565 citations

    5

    h-index

  5. MX
    Mo Xian

    Qingdao Institute of Bioenergy and Bioprocess Technology, China

    5 publications · 290 citations

    5

    h-index

1–5 of 1.4K

Institutions

376

  1. Chinese Academy of Sciences

    Beijing, China

    20 h-index

    162 publications

    8.7K citations

  2. Jiangnan University

    Wuxi, China

    17 h-index

    88 publications

    5.1K citations

  3. University of Chinese Academy of Sciences

    Beijing, China

    13 h-index

    49 publications

    2.7K citations

  4. East China University of Science and Technology

    Shanghai, China

    12 h-index

    74 publications

    3.8K citations

  5. Novo Nordisk Foundation

    Copenhagen, Denmark

    11 h-index

    41 publications

    3.7K citations

  6. Technical University of Denmark

    Kongens Lyngby, Denmark

    10 h-index

    40 publications

    3.2K citations

  7. Zhejiang University

    Hangzhou, China

    9 h-index

    52 publications

    4.1K citations

  8. Tianjin Institute of Industrial Biotechnology

    Tianjin, China

    8 h-index

    58 publications

    3K citations

1–8 of 376

Venues

  1. Metabolic Engineering

    21 publications · 1.9K citations

    17

    h-index

  2. ACS Synthetic Biology

    17 publications · 1.1K citations

    15

    h-index

  3. Microbial Cell Factories

    15 publications · 741 citations

    14

    h-index

  4. Nature Communications

    13 publications · 1.6K citations

    13

    h-index

  5. Biotechnology and Bioengineering

    13 publications · 928 citations

    13

    h-index

1–5