Concepedia

Mechanisms by which crystalline mannitol improves the reconstitution time of high concentration lyophilized protein formulations

Shreya S. Kulkarni, Raj Suryanarayanan, Joseph V. Rinella, Robin H. Bogner

European Journal of Pharmaceutics and Biopharmaceutics · 2018 · 50 citations · 27 references

Concepts

PharmacyBiochemistryPharmaceuticsLyophilizationPharmaceutical FormulationProtein BiochemistryFormulation Design For LyophilizationProtein LyophilizationProtein StructureStability Of Lyophilized ProductsConcentrationFormulation Development For LyophilizationLyophilization Process DevelopmentLyophilized Product FormulationProtein FormulationProtein Formulation EngineeringReconstitution TimeStability Of Protein Formulations

References

27

RESISTANCE OF SOLID SURFACES TO WETTING BY WATER

Robert N. Wenzel · Industrial & Engineering Chemistry · 1936 · 13K citations

Natural Sciences, Chemistry, Surface Engineering +10

The Dynamics of Capillary Flow

Edward W. Washburn · Physical Review · 1921 · 6.9K citations

Engineering, Physics, Fluid Dynamics +13

A. B. D. Cassie · Discussions of the Faraday Society · 1948 · 1.7K citations

Engineering, Materials Science, Mechanical Engineering +17

Challenges in the development of high protein concentration formulations

Zahra Shahrokh, Jun 军 Liu 刘 · Journal of Pharmaceutical Sciences · 2004 · 879 citations

Pharmacy, Pharmaceutics, Pharmacokinetics +12

Drop Penetration into Porous Powder Beds

Karen Hapgood, James D. Litster, Simon Biggs et al. · Journal of Colloid and Interface Science · 2002 · 302 citations · Full text

Natural Sciences, Materials Engineering, Surface Engineering +11