Aliskiren inhibits renin-mediated complement activation

Aliskiren Combined with Losartan in Type 2 Diabetes and Nephropathy

Hans‐Henrik Parving, Frederik Persson, Julia B. Lewis et al. · New England Journal of Medicine · 2008 · 1.1K citations · Full text

Medicine, Internal Medicine, Nephrology +11

Molecular Intercommunication between the Complement and Coagulation Systems

Umme Amara, Michael A. Flierl, Daniel Rittirsch et al. · The Journal of Immunology · 2010 · 723 citations · Full text

Life Sciences, Biochemistry, Immunology +14

C3 glomerulopathy: consensus report

Matthew C. Pickering, Vivette D. D’Agati, Carla Nester et al. · Kidney International · 2013 · 641 citations · Full text

Medicine, Nephrology, Pathology +17

Complement Activation and Inflammatory Processes in Drusen Formation and Age Related Macular Degeneration

Lincoln V. Johnson, William P. Leitner, Michelle K. Staples et al. · Experimental Eye Research · 2001 · 615 citations

Medicine, Immunology, Ophthalmology +17

Structure-based design of aliskiren, a novel orally effective renin inhibitor

Jeanette M. Wood, Jürgen Maibaum, Joseph Rahuel et al. · Biochemical and Biophysical Research Communications · 2003 · 503 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14