Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 16.7K citations · Full text

Crispr Rnas, Adaptive Bacterial Immunity, Crispr-associated Protein Cas9 +15

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor, Y. Bill Kim, Michael S. Packer et al. · Nature · 2016 · 5.2K citations · Full text

Engineering, Genetics, Synthetic Biology +11

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

Bernd Zetsche, Jonathan S. Gootenberg, Omar O. Abudayyeh et al. · Cell · 2015 · 4.7K citations · Full text

Rna Processing, Off-target Effect, Medicine +11

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

Nicole M. Gaudelli, Alexis C. Komor, Holly A. Rees et al. · Nature · 2017 · 4K citations · Full text

Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System

Baohui Chen, Luke A. Gilbert, Beth A. Cimini et al. · Cell · 2013 · 2K citations · Full text

Optimized Crispr/cas System, Dynamic Imaging, Genomic Loci +8