Acta Pharmacologica Sinica · 2018 · 42 citations · 34 references
MedicineOncologyPharmacologyCancer PharmacologyDrug DiscoveryMolecular OncologyHedgehog SignalingPersonalized Cancer TherapyPharmacodynamics Of Anticancer AgentsTargeted Cancer TherapyTargeted TherapyCanonical Hedgehog SignalingHedgehog MedicineHedgehog Pathway InhibitorsHedgehog Signaling InhibitionPharmacological Targeting Of Hedgehog SignalingSmo MutationsSmoothened Activation
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Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma
Daniel D. Von Hoff, Patricia LoRusso, Charles M. Rudin et al. · New England Journal of Medicine · 2009 · 1.1K citations · Full text
Medicine, Oncology, Pharmacology +17
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
D. Neil Watkins, David M. Berman, Scott G. Burkholder et al. · Nature · 2003 · 1.1K citations
A paracrine requirement for hedgehog signalling in cancer
Robert L. Yauch, Stephen E. Gould, Suzie J. Scales et al. · Nature · 2008 · 955 citations
Medicine, Cancer Biology, Oncology +14
<i>Smoothened</i> Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma
Robert L. Yauch, Gerrit J.P. Dijkgraaf, Bruno Alicke et al. · Science · 2009 · 844 citations · Full text
Medicine, Cancer Biology, Oncology +17