Stephen E. Gould

Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449

Charles M. Rudin, Christine L. Hann, John Laterra et al. · New England Journal of Medicine · 2009 · 1K citations · Full text

Neuro-oncology, Tumoral Pathology, Hedgehog Signaling +12

A paracrine requirement for hedgehog signalling in cancer

Robert L. Yauch, Stephen E. Gould, Suzie J. Scales et al. · Nature · 2008 · 952 citations

Cancer Research, Signaling Pathway, Medicine +6

<i>Smoothened</i> Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma

Robert L. Yauch, Gerrit J.P. Dijkgraaf, Bruno Alicke et al. · Science · 2009 · 837 citations · Full text

Health Sciences, Glioma, Genetics +14

MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade

Peter Ebert, Jeanne Cheung, Yagai Yang et al. · Immunity · 2016 · 714 citations · Full text

Cancer Immunosurveillance, Medicine, Receptor Tyrosine Kinase +6

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1+/−p53−/− mice

Justyna T. Romer, Hiromichi Kimura, Susan Magdaleno et al. · Cancer Cell · 2004 · 520 citations · Full text

Oncogenic Agent, Medicine, Cell Death +10